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F.A.Q. Section

Actos (Pioglitazone hydrochloride)

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Actos

Actos is an anti-diabetic medicine used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes by helping to restore body's proper response to insulin.

Other names for this medication:
Astrozone, Cereluc, CO Pioglitazone, Diabestat, Diaglit, Dom-Pioglitazone, G-Tase, Gen-Pioglitazone, Glita, Glizone, Glustin, Mint-Pioglitazone, Mylan-Pioglitazone, Novo-Pioglitazone, Opam, P-Glitz, Pepar, Tiazac, Zactos

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Also known as:  Pioglitazone hydrochloride.

Description

Actos is an effective drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes mellitus type 2.

Active ingredient of Actos is Pioglitazone.

Actos helps to keep your blood glucose levels within your target range by making your body more sensitive to insulin.

Actos decreases insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output.

Actos does not cause the body to make more insulin, therefore, when used alone, it does not cause low blood glucose (hypoglycemia).

Actos is used either alone or in combination with other anti-diabetic medications (such as insulin, metformin or a sulfonylurea such as glyburide).

Actos is not taken to treat type 1 diabetes.

Dosage

Actos is available in:

  • 15mg Min Dosage
  • 30mg Low Dosage

Take Actos by mouth with a full glass of water with or without food.

Usual dosage of Actos is 15 mg once a day.

In case of inadequate glycemic control, the dose can be increased up to 45 mg once daily.

If hypoglycemia occurs in a patient co-administered Actos and insulin, the dose of insulin should be decreased by 10% to 25%. Further adjustments to the insulin dose should be individualized based on glycemic response.

If you want to achieve most effective results do not stop taking Actos suddenly.

Missing a dose

Do not take double dose. If you miss a dose you should take it as soon as you remember about your missing. If it is the time for the next dose you should continue your regular dosing schedule.

Overdose

If you overdose Actos and you don't feel good you should visit your doctor or health care provider immediately. You can experience following symptoms of Actos overdosage: signs of low blood sugar, such as extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, and seizure (convulsions).

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

Actos has its side effects. The most common are:

  • cold symptoms such as stuffy nose, sneezing, cough, sore throat
  • headache
  • gradual weight gain
  • muscle pain
  • back pain
  • tooth problems

Less common but more serious side effects during taking Actos:

  • stomach pain, blood in your urine
  • painful urination
  • feeling short of breath, even with mild exertion
  • swelling or rapid weight gain
  • chest pain, general ill feeling
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes)
  • blurred vision
  • increased thirst or hunger, urinating more than usual
  • pale skin, easy bruising or bleeding, weakness

Side effects manifestations are not only depend on medicine you are taking but also depend on your health state and on the other factors.

Contra-indications

Do not take Actos if you are allergic to Actos components.

Do not take Actos if you are in a state of diabetic ketoacidosis.

Actos is ineffective and possibly harmful in treatment of type 1 diabetes.

Do not take Actos if you have congestive heart failure or heart disease, fluid retention, a history of bladder cancer, heart attack, stroke, liver disease, certain eye problem (macular edema) or polycystic ovary syndrome.

Avoid drinking alcohol. It lowers blood sugar and may interfere with your diabetes treatment.

Be careful with Actos if you are pregnant, planning to become pregnant, or are breast-feeding.

Do not use Actos in treatment of children under 18 years old.

Actos may increase the risk of bone fracture in women (usually in the upper arm, hand, or foot).

Actos can cause changes in the menstrual cycle (promote ovulation) and increase the risk of becoming pregnant

Do not take Actos for longer than recommended. Taking Actos for more than 1 year may increase your risk of developing bladder cancer.

Frequently asked questions

Q: What is Actos?

A: Actos is an effective drug of the class thiazolidinedione (TZD) with hypoglycemic (antihyperglycemic, antidiabetic) action to treat diabetes mellitus type 2.

Q: How does Actos work?

A: Actos helps to keep your blood glucose levels within your target range by making your body more sensitive to insulin. Actos decreases insulin resistance in the periphery and in the liver resulting in increased insulin-dependent glucose disposal and decreased hepatic glucose output.

Q: How long should I take Actos?

A: Do not take Actos for longer than recommended. Taking Actos for more than 1 year may increase your risk of developing bladder cancer.

Q: Can I take Actos to treat type 1 diabetes?

A: No. Actos is ineffective and possibly harmful in treatment of type 1 diabetes.

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